Method of “ion channel reconstitution in a planar lipid membrane (BLM)” is mostly used for:
- characterization of functional properties of intracellular ion channels
- recording of ion currents via open ion channels
- examination of one ion channel (one macromolecule) function
The principal topic of our research is functional regulation of the ryanodine receptor (RYR). It is one of the biggest intracellular Ca2+ channel that plays essential role in Ca2+ release from the lumen of intracellular stores to cytoplasm leading to muscle contraction.
Contact: Marta Gaburjáková, PhD.