Projects

Senior Research Fellow
RNDr. Denisa Imrichová, PhD.

National

Current
  • Use of recombinant enzymes with thioglucosidase activity for the transformation of plant glucosinolates and their analogues into biologically active substances with preventive and suppressive effect on neoplasia development
    Program: SRDA
    Duration: 1. 7. 2023 – 30. 6. 2027
  • -
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2026
  • Biochip systems for targeted glycan analysis of biomarkers for biomedical and biotechnological applications
    Program: SRDA
    Duration: 1. 7. 2021 – 30. 6. 2025
  • A new insight at isothiocyanates as substances interfering with the homeostasis of neoplastically transformed cells
    Program: VEGA
    Duration: 1. 1. 2021 – 31. 12. 2024
Finished
  • Defense mechanisms of microbial and animal cells in reducing their sensitivity to plant defensive compounds
    Program: SRDA
    Duration: 1. 7. 2020 – 30. 6. 2024
  • Multidrug resistance of leukemia cells - Phenotype caused by interference of multimodal molecular reasons
    Program: SRDA
    Duration: 1. 7. 2020 – 30. 6. 2024
  • Study of alteration in leukemia cells phenotype after induction of ABCB1 membrane transporter
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2022
  • Effect of endoplasmic reticulum-stress inducing substances on cell cycle regulatory mechanisms in cell lines with MDR phenotype
    Program: VEGA
    Duration: 1. 1. 2019 – 31. 12. 2021
  • The application of myrosinase for sulforaphane activation in development of a novel product exhibiting cancer prevention effects
    Program: SRDA
    Duration: 1. 7. 2017 – 30. 6. 2021
  • Study of changes in expression of some regulatory and functional proteins connected with the presence of P-gp protein in leukemic cells
    Program: VEGA
    Duration: 1. 1. 2017 – 31. 12. 2020
  • The effect of endoplasmic reticulum stress inductors and proteaosome inhibitors on leukemia cell line L1210, SKM-1 and MOLM-13 with induced P-glycoprotein overexpression
    Program: VEGA
    Duration: 1. 1. 2016 – 31. 12. 2018
  • Changes of leukemia cells drug sensitivity induced by changes of membrane drug transporters expression profile.
    Program: VEGA
    Duration: 1. 1. 2015 – 31. 12. 2018
Employees