Marta Gaburjáková, PhD.

Full CV
List of publications

Position:
Centre of Biosciences – Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences, Bratislava, Slovak Republic, Chief Research Fellow

Qualification:
1996 MSc., in Biophysics and  Molecular Physics, Faculty of  Mathematics and Physics, Comenius University, Bratislava, Slovak Republic  (supervisor: Waldemar Ziegler, PhD.)
title of diploma thesis: „ Lipid bilayers on the gel support – new type of model membrane“
2000 PhD., in Biophysics, Faculty of Mathematics and Physics, Comenius University, Bratislava, Slovak Republic (supervisor: Karol Ondriaš, DSc.)
title of thesis: „Modulation of functional properties of intracellular Ca2+ ion channels“
2004  Senior Research Fellow, Centre of Biosciences – Institute of Molecular Physiology and Genetics, Slovak Academy of Sciences, Bratislava, Slovak Republic

Techniques:
reconstitution of  ion channel  into the planar lipid membrane: RYR channel (native and recombinant), IP3R channel (native and recombinant), Cl- channel (native),  isolation of microsomal preparation from animal muscle tissue (rat, mouse, dog, human) and HEK293 cells, analysis of electrophysiological signals, bioinformatics analysis of proteins, fluorescence spectroscopy, skill in writing research proposals and scientific papers

Support:

Slovak Research and Development Agency (APVV):
APVV-21-0473
Mutations associated with Wolfram syndrome: Alternative signaling pathways for calcium and mitochondrial physiology (2022 – 2026)
principal investigator: RNDr. Michal Cagalinec, PhD., co-investigator
APVV-20-0202
Activation of the VGF/BDNF/TrkB pathway by synthetic mRNA encapsulated in polyplex nanoparticles: effects on neural excitability, neuroplasticity and animal behavior (2021 – 2025)
principal investigator: MMedSc. Dremencov Eliyahu DrSc., co-investigator
APVV-19-0435
Novel antidepressant therapy – long term consequencies on offspring (2020 – 2024)
principal investigator: prof. RNDr. Lacinová Ľubica DrSc., co-investigator

Grant Agency for Science (VEGA):
VEGA 2/0018/21
The role of protein-protein interactions in regulation of the cardiac ryanodine receptor (2021 – 2024)
principal investigator: Mgr. Jana Gaburjáková, PhD., vice-principal investigator
VEGA 2/0008/20
Regulation of ryanodine receptors (RYR) from the rat brain under physiological and pathophysiological conditions (2020 – 2023)
principal investigator
The role of physiologically relevant metal ions Mg2+ and Zn2+ in the luminal regulation of the cardiac ryanodine receptor  (2015 – 2017)
principal investigator: Mgr. Jana Gaburjáková, PhD., vice-principal investigator
The role of calsequestrin in luminal regulation of the cardiac ryanodine receptor (2014 – 2016)
principal investigator