We study the function of the ryanodine (RYR) receptor. The RYR is one of the largest of the intracellular ion channels. Its role is to regulate the release of Ca2+ ions from the lumen of intracellular stores into the cytoplasm of the cell, thereby triggering the contraction of the muscle cell.
The method of “reconstitution of ion channels in planar lipid membrane (BLM)” is mainly used:
- to characterise the functional properties of intracellular ion channels
- to record the flux of ions that flow through an open channel
- to study the function of a single channel – a single macromolecule
Contact: Mgr. Marta Gaburjáková, PhD.
Support: NIH FIRCA R03 TW 00949, ITMS 26240120008 a ITMS 26230120006
